SQLSTATE[HY000] [2002] Connection refused

FILE: /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Db/Driver.class.php 　LINE: 106

#0 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Db/Driver.class.php(106): E('SQLSTATE[HY000]...')
#1 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Db/Driver.class.php(1038): Think\Db\Driver->connect()
#2 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Db/Driver/Mysql.class.php(50): Think\Db\Driver->initConnect(true)
#3 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Model.class.php(126): Think\Db\Driver\Mysql->getFields('ot_config')
#4 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Model.class.php(114): Think\Model->flush()
#5 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Model.class.php(1416): Think\Model->_checkTableInfo()
#6 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Model.class.php(89): Think\Model->db(0, '', true)
#7 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Common/functions.php(534): Think\Model->__construct('Config', '', '')
#8 /web/www/otxt/www.mixianchao.com/Core/Application/Common/Api/ConfigApi.class.php(20): M('Config')
#9 /web/www/otxt/www.mixianchao.com/Core/Application/Common/Common/function.php(977): Common\Api\ConfigApi::lists()
#10 /web/www/otxt/www.mixianchao.com/Core/Application/Home/Controller/Home.php(91): api('Config/lists')
#11 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Controller.class.php(41): Home\Controller\Home->_initialize()
#12 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Common/functions.php(584): Think\Controller->__construct()
#13 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/App.class.php(69): controller('Index', '')
#14 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/App.class.php(164): Think\App::exec()
#15 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/Library/Think/Think.class.php(98): Think\App::run()
#16 /web/www/otxt/www.mixianchao.com/Core/ThinkPHP/ThinkPHP.php(94): Think\Think::start()
#17 /web/www/otxt/www.mixianchao.com/static/index.php(18): require('/web/www/otxt/w...')
#18 {main}